The CDC says FluMist isn;t working well.Flu Vaccines 60 Percent Effective This Year. Depending on the season, it kills anywhere between 4,000 and 50,000 people a year in the United States.The flu vaccines on the market deliver a cocktail to protect against three or four strains of flu. In light of the,"Several trials have reported that LAIVs can boost virus-specific CTLs as well as mucosal and serum antibodies and provide broad cross-protection against heterologous human influenza A viruses." FLUMIST QUADRIVALENT may not protect all individuals receiving the vaccine; The most common solicited adverse reactions (occurring ≥10% in vaccine recipients and at least 5% greater than in placebo) reported were runny nose or nasal congestion in persons 2-49 years, fever >100°F in children 2-6 years, and sore throat in adults 18-49 years. You may hear it called by its brand name, FluMist.Unlike the flu shot, there are no needles involved.That’s a good thing, especially to parents whose kids can’t stand the sight of needles. Now.The cold-adapted influenza vaccine version of the vaccine is called CAIV-T, and is stable for storage in a refrigerator, rather than requiring freezer storage as did the originally-approved formulation. Their effectiveness varies from year to year and they must be made fresh each flu season to match circulating strains of influenza, which also change.FluMist, made by MedImmune, uses live but weakened strains of flu virus to stimulate the immune system. FluMist, made by MedImmune, uses live but weakened strains of flu virus to stimulate the immune system. ".But the Advisory Committee on Immunization Practices reviewed the data from the past few flu seasons and found it didn’t work in recent years. in this January 10, 2013 file photo. It’s sprayed up the nose and in some seasons it had been reported to be more effective than some injected vaccines.“Nasal spray flu vaccine accounts for about one-third of all flu vaccines given to children. It says it’s not clear why it hasn’t worked well.“In comparison, inactivated influenza vaccine (flu shots) had a vaccine effectiveness estimate of 63 percent against any flu virus among children 2 years through 17 years.”.AstraZeneca, which owns MedImmune, said other research contradicts ACIP's and the CDC's findings. "AstraZeneca is working with the CDC to better understand its data to help ensure eligible patients continue to receive the vaccine in future seasons in the U.S.," it said.Flu usually hits the very young and the very old the hardest. Get a Flu Vaccine. Related Pages . Listing a study does not mean it has been evaluated by the U.S. Federal Government. Live attenuated influenza vaccine (LAIV) is a type of influenza vaccine in the form of a nasal spray that is recommended for the prevention of influenza. In 2016, the CDC recommended that LAIV not be used for the 2016-2017 flu season and instead another type of influenza vaccine be used.However, in February 2018, the CDC Advisory Committee on Immunization Practices (ACIP) reinstated the use of LAIV for the 2018-2019 flu season.The use of LAIV is contraindicated, and should therefore not be used, in the following populations:The live attenuated vaccine is based on a flu strain that does not cause disease, that replicates well at relatively cold temperatures (about 25 °C, for incubation purposes), and replicates poorly at body temperature (which minimizes risk to humans). An official website of the United States government,Recalls, Market Withdrawals and Safety Alerts,Questions and Answers - FluMist Quadrivalent (Influenza Virus Vaccine Live, Intranasal).Individuals who have had a severe allergic reaction to any component of FluMist Quadrivalent, including egg protein, gentamicin, gelatin, and arginine, after a previous dose of any influenza vaccine.Children and adolescents ages 2 through 17 years who are receiving aspirin or aspirin containing therapy, because of the association of Reye’s syndrome with aspirin and influenza infection. We also discuss the benefits, risks, and side effects of flu shots, and who should avoid them. FluMist Quadrivalent is manufactured in the same way as FluMist (trivalent) vaccine.