Thiomersal is very toxic by inhalation, ingestion, and in contact with skin (EC hazard symbol T+), with a danger of cumulative effects. Epub 2019 Nov 5.Dreskin SC, Halsey NA, Kelso JM, Wood RA, Hummell DS, Edwards KM, Caubet JC, Engler RJ, Gold MS, Ponvert C, Demoly P, Sanchez-Borges M, Muraro A, Li JT, Rottem M, Rosenwasser LJ.World Allergy Organ J. However, new studies prove that this is not the case.The main route of human exposure to MeHg is oral ingestion of seafood; for ethylmercury, human exposure is mainly by injection of thimerosal-containing vaccines.
Epub 2019 Nov 5.Johnson R, Kernerman SM, Sawtelle BG, Rastogi SC, Nielsen HS, Ampel NM.Mycopathologia. Some of the products that are preserved using thimerosal include cosmetics such as mascara, eye shadows and makeup remover; and personal hygiene items such as antiseptic sprays, soap-free cleansers and topical medications. Research does not show any link between thimerosal in vaccines and autism, a neurodevelopmental disorder. Thiomersal allergy and vaccination reactions. In some production processes thiomersal is used in the inactivation of vaccine antigen together with heat, for example in the manufacture of whole cell pertussis vaccine. 2005;28(2):89-101. doi: 10.2165/00002018-200528020-00001.Drug Saf. Thiomersal (also know as thimerosal, merthiolate) is an organomercurial derivative of ethylmercury that has been used very widely, and for a very long time, as a preservative in vaccines in their bulk formulations. If you are unsure, ask your pharmacist for assistance.Whenever you are being treated or vaccinated against a certain medical condition, inform your doctor that you’ve got a thimerosal allergy. This means more choices than ever for peanut-allergic shoppers and...©2020 PeanutAllergy.com. Although this reaction has contributed to concerns about vaccine safety, it was not a major force leading to the recommendation by the authorities in some countries for the elimination of thiomersal from vaccines. When thimerosal enters the body, it breaks down to ethylmercury and thiosalicylate, which are readily eliminated.Thimerosal use in medical products has a record of being very safe. 2009 Jul;14(3):166-72. doi: 10.1111/j.1744-6155.2009.00194.x.Stone CA Jr, Rukasin CRF, Beachkofsky TM, Phillips EJ.Br J Clin Pharmacol. There is no scientific evidence to support this claim. Thimerosal may also be used in the early stages of manufacturing for a few vaccines but is removed during processing, with only trace (insignificant) amounts remaining. This involves ingesting oral antihistamine or topical application of hydrocortisone on the affected part.Once you have been diagnosed with thimerosal sensitivity, you should avoid contact with any product that has been preserved with thiomersal. Sensitization to thimerosal is associated with routine vaccination and this sensitization is lifelong. These concerns have been based primarily on data regarding the toxicity of a related substance, methylmercury, and from data on chronic exposure to mercury from the food chain.Such safety concerns have led to initiatives in some countries to eliminate, reduce or replace thiomersal in vaccines, both in single dose and multidose presentations.
Epub 2012 Jun 6.Drug Saf. 2012 Dec;174(5-6):353-8. doi: 10.1007/s11046-012-9555-6. Delayed hypersensitivity to thiomersal was demonstrated in 1% of individuals attending the Contact Dermatitis Investigation Unit, and 50 of these patients with positive patch tests to thiomersal were studied.
2019 Dec;85(12):2694-2706. doi: 10.1111/bcp.14112. Please enable it to take advantage of the complete set of features!Clipboard, Search History, and several other advanced features are temporarily unavailable.National Center for Biotechnology Information,Unable to load your collection due to an error,Unable to load your delegates due to an error.McMahon AW, Iskander JK, Haber P, Braun MM, Ball R.Vaccine. Delayed hypersensitivity to thiomersal was demonstrated in 1% of individuals attending the Contact Dermatitis Investigation Unit, and 50 of these patients with positive
Epub 2010 Dec 23.J Spec Pediatr Nurs. neomycin) in vaccines have been reported.Thimerosal is an organic mercurial compound in use since the 1930s and added to certain immunobiologic products as a preservative. According to the CDC, thimerosal is “a mercury-containing compound” used as a preservative in multi-dose flu vaccines to prevent contamination ( here). 2010 Nov-Dec;65(6):533-41. doi: 10.2515/therapie/2010069. There is no evidence of harm caused by the low doses of thimerosal in vaccines, except for minor reactions like redness and swelling at the injection site. 2006 Jan;5(1):17-29. doi: 10.1517/14740338.5.1.17.Stone CA Jr, Rukasin CRF, Beachkofsky TM, Phillips EJ.Br J Clin Pharmacol. COVID-19 is an emerging, rapidly evolving situation.Thiomersal is the preservative in all toxoid vaccines routinely administered to children in the UK, but exposure from other sources is uncommon. 2019 Dec;85(12):2694-2706. doi: 10.1111/bcp.14112. In the body, it is metabolized or degraded to ethylmercury (C2H5Hg ) and thiosalicylate.